Annotated protein: | Leucine-rich repeat and fibronectin type-III domain-containing protein 2. Gene symbol: LRFN2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q460M5 |
antibody wiki: | |
SynGO gene info: | SynGO data @ LRFN2 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
Synapse type(s): | brain |
Annotated paper: | Wang CY, et al. "A novel family of adhesion-like molecules that interacts with the NMDA receptor" J Neurosci. 2006 Feb 22;26(8):2174-83 PMID:16495444 |
Figure(s): | Fig 2 |
Annotation description: | LRFN2 was enriched in postsynaptic density fractions. 15/01/2018 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
Evidence tracking, Biological System: | Intact tissue Non-neuronal tissue |
Evidence tracking, Protein Targeting: | Over-expression Antibody (detection) |
Evidence tracking, Experiment Assay: | Western blot Biochemical fractionation (generic) IP + WB/MSMS |
Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
SynGO annotation ID: | 2214 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |