| Annotated protein: | Homer protein homolog 3 (Homer-3). Gene symbol: HOMER3. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q99JP6 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ HOMER3 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | cerebellum, glutamatergic hippocampus, glutamatergic |
| Annotated paper: | Tao-Cheng JH, et al. "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation" Neuroscience. 2014 Apr 25;266:80-90 PMID:24530450 |
| Figure(s): | Figure 3-6 |
| Annotation description: | Homer 3 antibody clearly labeled the PSDs of mossy fiber synapses in the CA3 region of the hippocampus and synapses on Purkinje spines, but not PSDs in the stratum radiatum of the CA1 area and the cerebral cortex. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
| Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
| SynGO annotation ID: | 221 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |