Annotated protein: | Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2). Gene symbol: HOMER2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9QWW1 |
antibody wiki: | |
SynGO gene info: | SynGO data @ HOMER2 |
Ontology domain: | Cellular Component |
SynGO term: | postsynaptic density (GO:0014069) |
Synapse type(s): | hippocampus, glutamatergic cerebral cortex, glutamatergic |
Annotated paper: | Tao-Cheng JH, et al. "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation" Neuroscience. 2014 Apr 25;266:80-90 PMID:24530450 |
Figure(s): | Figures 2-6 |
Annotation description: | Homer 2 antibody strongly labeled the PSDs in the stratum radiatum of the CA1 area (Fig. 3) and the cerebral cortex |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
SynGO annotation ID: | 220 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |