Annotated protein:Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2). Gene symbol: HOMER2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9QWW1
antibody wiki:
SynGO gene info:SynGO data @ HOMER2
Ontology domain:Cellular Component
SynGO term:postsynaptic density (GO:0014069)
Synapse type(s):hippocampus, glutamatergic
cerebral cortex, glutamatergic
Annotated paper:Tao-Cheng JH, et al. "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation" Neuroscience. 2014 Apr 25;266:80-90 PMID:24530450
Figure(s):Figures 2-6
Annotation description:Homer 2 antibody strongly labeled the PSDs in the stratum radiatum of the CA1 area (Fig. 3) and the cerebral cortex
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Harold MacGillavry (ORCID:0000-0002-6153-3586)
Casper Hoogenraad (ORCID:0000-0002-2666-0758)
Lab:Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands
SynGO annotation ID:220
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology