| Annotated protein: | Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (104 kDa diacylglycerol kinase) (DGK-IV) (Diglyceride kinase zeta) (DGK-zeta). Gene symbol: DGKZ. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O08560 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ DGKZ |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density (GO:0014069) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Kim K, et al. "Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance" EMBO J. 2009 Apr 22;28(8):1170-9 PMID:19229292 |
| Figure(s): | fig 1G, fig 2G |
| Annotation description: | DGKZ was enriched in postsynaptic density fractions. DGKZ was localized in in cell bodies, dendrites, and dendritic spines. 26/01/2018 Pim - DGKZ interacts and colocalizes with PSD-95. |
| Evidence tracking, Biological System: | Intact tissue Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Confocal Western blot Biochemical fractionation (generic) IP + WB/MSMS |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2193 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |