| Annotated protein: | Breakpoint cluster region protein (EC 2.7.11.1). Gene symbol: BCR. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: F1LXF1 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ BCR |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic density, intracellular component (GO:0099092) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Oh D, et al. "Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins" J Neurosci. 2010 Oct 20;30(42):14134-44 PMID:20962234 |
| Figure(s): | fig 1, 2F, 2I |
| Annotation description: | BCR was enriched in postsynaptic density fractions. BCR was localized in spines and dendrites. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Western blot Biochemical fractionation (generic) IP + WB/MSMS |
| Annotator(s): | Hwajin Jung (ORCID:0000-0001-6194-9648) Eunjoon Kim (ORCID:0000-0001-5518-6584) |
| Lab: | Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS) and Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea |
| SynGO annotation ID: | 2192 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |