Annotated protein:Homer protein homolog 1 (PSD-Zip45) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1). Gene symbol: HOMER1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9Z214
antibody wiki:
SynGO gene info:SynGO data @ HOMER1
Ontology domain:Cellular Component
SynGO term:postsynaptic density (GO:0014069)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Tu JC, et al. "Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins" Neuron. 1999 Jul;23(3):583-92 PMID:10433269
Figure(s):Figure 6
Annotation description:This paper identifies Homer1b/c as a Shank-interacting protein and uses immuno-EM to demonstrate localization in the PSD.

Note: HOMER1a does not have this CC (see SynGO ticket #239).

9/3/2017 Pim:
-Homer1b/c isoforms are different from Homer1a. I have made this annotation against the general Homer1 protein accession since this describes the general idea on the homer gene localization.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Harold MacGillavry (ORCID:0000-0002-6153-3586)
Casper Hoogenraad (ORCID:0000-0002-2666-0758)
Lab:Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands
SynGO annotation ID:219
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology