Annotated protein:Gamma-aminobutyric acid type B receptor subunit 1 isoform a. Gene symbol: GABBR1. Taxonomy: Macaca Mulatta (Rhesus Macaque). Uniprot ID: H9FSF4
antibody wiki:
SynGO gene info:SynGO data @ GABBR1
Ontology domain:Cellular Component
SynGO term:integral component of presynaptic active zone membrane (GO:0099059)
Synapse type(s):globus pallidus, glutamatergic
Annotated paper:Charara A, et al. "Synaptic and extrasynaptic GABA-A and GABA-B receptors in the globus pallidus: an electron microscopic immunogold analysis in monkeys" Neuroscience. 2005;131(4):917-33 PMID:15749345
Figure(s):Fig.5
Annotation description:Fig.5: "The majority of GABA-BR1 gold particles are located in the presynaptic grid of the asymmetric synapse (arrows), although a few particles could be seen at non-synaptic sites."
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2176
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology