Annotated protein: | Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2). Gene symbol: GABRA2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P23576 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GABRA2 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of postsynaptic specialization membrane (GO:0099060) |
Synapse type(s): | hippocampus, GABAergic |
Annotated paper: | Kasugai Y, et al. "Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling" Eur J Neurosci. 2010 Dec;32(11):1868-88 PMID:21073549 |
Figure(s): | Fig.4 |
Annotation description: | Fig.4: "Localisation of the alpha2 subunit of the GABAA receptor in a synapse on an axon initial segment" |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 2172 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |