Annotated protein:Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2). Gene symbol: GABRA2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P23576
antibody wiki:
SynGO gene info:SynGO data @ GABRA2
Ontology domain:Cellular Component
SynGO term:integral component of postsynaptic specialization membrane (GO:0099060)
Synapse type(s):hippocampus, GABAergic
Annotated paper:Kasugai Y, et al. "Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling" Eur J Neurosci. 2010 Dec;32(11):1868-88 PMID:21073549
Figure(s):Fig.4
Annotation description:Fig.4: "Localisation of the alpha2 subunit of the GABAA receptor in a synapse on an axon initial segment"
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2172
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology