| Annotated protein: | Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3). Gene symbol: GABRB3. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P63079 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GABRB3 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Kasugai Y, et al. "Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling" Eur J Neurosci. 2010 Dec;32(11):1868-88 PMID:21073549 |
| Figure(s): | Fig.2, 3 |
| Annotation description: | Fig.2: "Extrasynaptic labelling for the beta3 subunit (e.g. arrows) on an apical dendrite and in an emerging spine (s, arrows)." Fig.3: "Synaptic and extrasynaptic labelling for the beta3 subunit of the GABAA receptor on a main apical dendrite and a small oblique dendrite in stratum radiatum." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2170 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |