Annotated protein: | Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta). Gene symbol: GABRD. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P18506 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GABRD |
Ontology domain: | Cellular Component |
SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Aoki C, et al. "Adolescent female rats exhibiting activity-based anorexia express elevated levels of GABA(A) receptor alpha4 and delta subunits at the plasma membrane of hippocampal CA1 spines" Synapse. 2012 May;66(5):391-407 PMID:22213233 |
Figure(s): | Fig.5, 6 |
Annotation description: | Fig.5: "Electron microscopy confirmed that δ subunits also occur non-synaptically along the plasma membrane of dendritic shafts and spines as well as intracellularly (Fig. 5)" |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Pim van Nierop (ORCID:0000-0003-0593-3443) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 2168 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |