Annotated protein:Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta). Gene symbol: GABRD. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P18506
antibody wiki:
SynGO gene info:SynGO data @ GABRD
Ontology domain:Cellular Component
SynGO term:integral component of postsynaptic membrane (GO:0099055)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Aoki C, et al. "Adolescent female rats exhibiting activity-based anorexia express elevated levels of GABA(A) receptor alpha4 and delta subunits at the plasma membrane of hippocampal CA1 spines" Synapse. 2012 May;66(5):391-407 PMID:22213233
Figure(s):Fig.5, 6
Annotation description:Fig.5: "Electron microscopy confirmed that δ subunits also occur non-synaptically along the plasma membrane of dendritic shafts and spines as well as intracellularly (Fig. 5)"
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Pim van Nierop (ORCID:0000-0003-0593-3443)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2168
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology