Annotated protein: | Glutamate receptor-interacting protein 1 (GRIP-1) (AMPA receptor-interacting protein GRIP1). Gene symbol: GRIP1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P97879 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GRIP1 |
Ontology domain: | Cellular Component |
SynGO term: | postsynapse (GO:0098794) |
Annotated paper: | Dong H, et al. "GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors" Nature. 1997 Mar 20;386(6622):279-84 PMID:9069286 |
Figure(s): | Figure 4 |
Annotation description: | Immunostaining with an antibody specific for GRIP1 demonstrates a punctate pattern co-localizing with AMPARs at postsynaptic sites indicating that GRIP1 is enriched at postsynaptic specializations. |
Evidence tracking, Biological System: | Cultured neurons |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Wide-field fluorescence |
Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
SynGO annotation ID: | 216 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |