| Annotated protein: | Integrin beta-1 (Beta oligodendroglia) (Beta OL) (Fibronectin receptor subunit beta) (VLA-4 subunit beta) (CD antigen CD29). Gene symbol: ITGB1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P49134 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ ITGB1 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Babayan AH, et al. "Integrin dynamics produce a delayed stage of long-term potentiation and memory consolidation" J Neurosci. 2012 Sep 12;32(37):12854-61 PMID:22973009 |
| Figure(s): | figure 1 |
| Annotation description: | Fig.1 Detected in spine with antibodies that detect activated β1 integrin (Act-β1) - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2154 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |