Annotated protein: | Syntaxin-3. Gene symbol: STX3. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q64704 |
antibody wiki: | |
SynGO gene info: | SynGO data @ STX3 |
Ontology domain: | Cellular Component |
SynGO term: | postsynapse (GO:0098794) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Jurado S, et al. "LTP requires a unique postsynaptic SNARE fusion machinery" Neuron. 2013 Feb 6;77(3):542-58 PMID:23395379 |
Figure(s): | Fig.2 |
Annotation description: | Fig.2: "Postsynaptic Stx-3 KD in vivo Does Not Alter Basal Synaptic Transmission or Constitutive Recycling" - Subcellular localization of STX3 observed in dendrites using structured illumination microscopy: "Stx-3 was often found adjacent to PSD-95 puncta, consistent with recent studies using immunogold labeling of syntaxins in hippocampal slices and cultured neurons (J.H. Tao-Cheng et al., 2012, Soc. Neurosci., abstract)." |
Evidence tracking, Biological System: | Cultured neurons |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Super resolution |
Annotator(s): | Momchil Ninov (ORCID:0000-0002-0808-7003) Mahdokht Kohansalnodehi (ORCID:0000-0002-3898-5197) Reinhard Jahn (ORCID:0000-0003-1542-3498) |
Lab: | Department of Neurobiology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany |
SynGO annotation ID: | 2151 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |