Annotated protein:Syntaxin-3. Gene symbol: STX3. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q64704
antibody wiki:
SynGO gene info:SynGO data @ STX3
Ontology domain:Cellular Component
SynGO term:postsynapse (GO:0098794)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Jurado S, et al. "LTP requires a unique postsynaptic SNARE fusion machinery" Neuron. 2013 Feb 6;77(3):542-58 PMID:23395379
Figure(s):Fig.2
Annotation description:Fig.2: "Postsynaptic Stx-3 KD in vivo Does Not Alter Basal Synaptic Transmission or Constitutive Recycling"
- Subcellular localization of STX3 observed in dendrites using structured illumination microscopy: "Stx-3 was often found adjacent to PSD-95 puncta, consistent with recent studies using immunogold labeling of syntaxins in hippocampal slices and cultured neurons (J.H. Tao-Cheng et al., 2012, Soc. Neurosci., abstract)."
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Super resolution
Annotator(s):Momchil Ninov (ORCID:0000-0002-0808-7003)
Mahdokht Kohansalnodehi (ORCID:0000-0002-3898-5197)
Reinhard Jahn (ORCID:0000-0003-1542-3498)
Lab:Department of Neurobiology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany
SynGO annotation ID:2151
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology