| Annotated protein: | Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2). Gene symbol: PTK2B. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P70600 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ PTK2B |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Babayan AH, et al. "Integrin dynamics produce a delayed stage of long-term potentiation and memory consolidation" J Neurosci. 2012 Sep 12;32(37):12854-61 PMID:22973009 |
| Figure(s): | figure 1 |
| Annotation description: | Fig.1 Detected in spine with antibodies that detect activated FAK2 (pPyk2) anti-Pyk2 antibody (#05-488) @ http://www.merckmillipore.com/NL/en/product/Anti-Pyk2/CAK-Antibody-clone-74,MM_NF-05-488 |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2131 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |