| Annotated protein: | Metabotropic glutamate receptor 1 (mGluR1). Gene symbol: GRM1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P23385 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GRM1 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic density membrane (GO:0099061) |
| Synapse type(s): | hippocampus, glutamatergic cerebellum, glutamatergic |
| Annotated paper: | Baude A, et al. "The metabotropic glutamate receptor (mGluR1 alpha) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction" Neuron. 1993 Oct;11(4):771-87 PMID:8104433 |
| Figure(s): | Figure 4, 6 |
| Annotation description: | This paper describes immuno-EM data demonstrating that in hippocampus and cerebellum of rats, mGluR1 is preferentially localized at the periphery of the postsynaptic density. 24/2/2017 Pim "integral component ..." term derived from TM domains in protein. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
| Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
| SynGO annotation ID: | 213 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |