| Annotated protein: | Huntingtin interacting protein 1. Gene symbol: HIP1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: G3V8Y8 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ HIP1 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Yao PJ, et al. "Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy" J Comp Neurol. 2006 Jan 10;494(2):368-79 PMID:16320245 |
| Figure(s): | figure 3, 5 |
| Annotation description: | HIP1 immunolabeling demonstrated a presynaptic localization. 11/12/2017 Pim: - Fig.3: "HIP1 immunoreactivity is found in the postsynaptic profiles more often than in the presynaptic profiles" - Fig.5: "HIP1 immunolabeling, like epsin1, was frequently found to be close to, or even physically associated with, the plasma membrane (Fig. 5)"...."HIP1 immunolabeling is concentrated at the plasma membrane of the postsynaptic profiles but is distributed evenly in the presynaptic profiles." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 2125 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |