Annotated protein:Rho GTPase-activating protein 44 (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2). Gene symbol: ARHGAP44. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: F1LQX4
antibody wiki:
SynGO gene info:SynGO data @ ARHGAP44
Ontology domain:Cellular Component
SynGO term:presynaptic active zone (GO:0048786)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Raynaud F, et al. "Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation" J Neurosci. 2013 Jun 5;33(23):9699-715 PMID:23739967
Figure(s):figure 1
Annotation description:Fig.1F The authors do not mention the active zone themselves. However, active zone localization is observed by the annotator.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Frank Koopmans (ORCID:0000-0002-4973-5732)
Guus Smit (ORCID:0000-0002-2286-1587)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:2124
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology