Annotated protein: | Rho GTPase-activating protein 44 (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2). Gene symbol: ARHGAP44. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: F1LQX4 |
antibody wiki: | |
SynGO gene info: | SynGO data @ ARHGAP44 |
Ontology domain: | Cellular Component |
SynGO term: | presynaptic active zone (GO:0048786) |
Synapse type(s): | hippocampus, glutamatergic |
Annotated paper: | Raynaud F, et al. "Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation" J Neurosci. 2013 Jun 5;33(23):9699-715 PMID:23739967 |
Figure(s): | figure 1 |
Annotation description: | Fig.1F The authors do not mention the active zone themselves. However, active zone localization is observed by the annotator. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Frank Koopmans (ORCID:0000-0002-4973-5732) Guus Smit (ORCID:0000-0002-2286-1587) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 2124 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |