| Annotated protein: | Ras-related protein Rab-8A (EC 3.6.5.2). Gene symbol: RAB8A. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P35280 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RAB8A |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | brain |
| Annotated paper: | Wilhelm BG, et al. "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins" Science. 2014 May 30;344(6187):1023-8 PMID:24876496 |
| Figure(s): | Table S2 |
| Annotation description: | Quantitative mass spectrometric analyses (iBAQ) of purified synaptosomes indicate the presence of Rab8A in presynaptic terminals. 28/8/2017 Pim - Data does not distinguish pre- from postsynaptic localization. 'synapse (GO:0045202)' term selected instead of 'presynapse'. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | none of the above |
| Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
| Annotator(s): | John Chua (ORCID:0000-0002-5615-1014) |
| Lab: | Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Neurobiology/Ageing Program, Life Sciences Institute, National University of Singapore and Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore |
| Additional literature: | Mass spectrometric analyses of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting identify the presence of Rab8A in these fractions. @ PMID:24413018 |
| SynGO annotation ID: | 206 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |