| Annotated protein: | Sorting nexin-1. Gene symbol: SNX1. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q9WV80 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SNX1 |
| Ontology domain: | Cellular Component |
| SynGO term: | extrinsic component of postsynaptic endosome membrane (GO:0098999) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Fukaya M, et al. "EFA6A, a guanine nucleotide exchange factor for Arf6, interacts with sorting nexin-1 and regulates neurite outgrowth" J Neurochem. 2014 Apr;129(1):21-36 PMID:24261326 |
| Figure(s): | Fig 6 |
| Annotation description: | Quantitative immunogold reactivity against SNX1 in mouse hippocampal pyramidal neurons shows a predominant postsynaptic distribution. SNX1 is localized to endosome membranes, but the subclass of endosome (early/late/recycling) is not unambiguously determined |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Jan van Weering (ORCID:0000-0001-5259-4945) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 203 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |