| Annotated protein: | Clathrin coat assembly protein AP180 (91 kDa synaptosomal-associated protein) (Clathrin coat-associated protein AP180). Gene symbol: SNAP91. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q05140 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SNAP91 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic membrane (GO:0045211) |
| Synapse type(s): | Schaffer collateral synapse (CA3->CA1) Parallel fibre (cerebellum -> Purkinje-cell) |
| Annotated paper: | Yao PJ, et al. "Synaptic distribution of the endocytic accessory proteins AP180 and CALM" J Comp Neurol. 2005 Jan 3;481(1):58-69 PMID:15558718 |
| Figure(s): | figures 3,5 |
| Annotation description: | In figures 3 and 5, the authors use immunogold electron microscopy to localize AP180 in rat synapses. Figure 3 is synapses from CA1 neurons and figure 5 is synapses from cerebellar granule cells on Purkinje neurons. 6/12/2017 Pim - The plasma membrane term of the postsynapse was selected as inferred canonical site of action for clathrin coat recruitment. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Peter McPherson (ORCID:0000-0001-7806-5662) |
| Lab: | Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada |
| Additional literature: | Similar findings. @ PMID:17640037 |
| SynGO annotation ID: | 2004 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |