Annotated protein:Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein) (rCALM). Gene symbol: PICALM. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O55012
antibody wiki:
SynGO gene info:SynGO data @ PICALM
Ontology domain:Cellular Component
SynGO term:postsynapse (GO:0098794)
Synapse type(s):Schaffer collateral synapse (CA3->CA1)
Parallel fibre (cerebellum -> Purkinje-cell)
Annotated paper:Yao PJ, et al. "Synaptic distribution of the endocytic accessory proteins AP180 and CALM" J Comp Neurol. 2005 Jan 3;481(1):58-69 PMID:15558718
Figure(s):figures 4, 6
Annotation description:In figures 4 and 6, the authors use immunogold electron microscopy to localize CALM in rat synapses. Figure 4 is synapses from CA1 neurons and figure 6 is synapses from cerebellar granule cells on Purkinje neurons.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Peter McPherson (ORCID:0000-0001-7806-5662)
Lab:Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada
SynGO annotation ID:2003
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology