| Annotated protein: | Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4). Gene symbol: SH3GL2. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q62420 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SH3GL2 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynaptic cytosol (GO:0099523) |
| Synapse type(s): | Photoreceptor ribbon synapse |
| Annotated paper: | Wahl S, et al. "A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons" J Neurosci. 2013 Jun 19;33(25):10278-300 PMID:23785143 |
| Figure(s): | figure 7 |
| Annotation description: | Endophilin was diffusely distributed throughout the entire presynaptic terminal (Fig. 7A-E)." The authors use conventional light microscopy and discover that "endophilin is diffusely distributed throughout the presynaptic terminal and is not particularly enriched around the synaptic ribbon. All micrographs were obtained by conventional imaging". |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Peter McPherson (ORCID:0000-0001-7806-5662) |
| Lab: | Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada |
| SynGO annotation ID: | 2002 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |