Annotated protein:Amphiphysin. Gene symbol: AMPH. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q7TQF7
antibody wiki:
SynGO gene info:SynGO data @ AMPH
Ontology domain:Cellular Component
SynGO term:presynaptic endocytic zone (GO:0098833)
Synapse type(s):Photoreceptor ribbon synapse
Annotated paper:Wahl S, et al. "A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons" J Neurosci. 2013 Jun 19;33(25):10278-300 PMID:23785143
Figure(s):figure 6
Annotation description:The authors use light microscopy to localize amphiphysin in mouse photoreceptor cells. The protein is found in the synaptic layers of the retina in close proximity to the synaptic ribbon, the release site in these neurons. Gigure 6 uses super resolution SIM microscopy.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Super resolution
Annotator(s):Peter McPherson (ORCID:0000-0001-7806-5662)
Lab:Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada
SynGO annotation ID:2001
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology