| Annotated protein: | Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor). Gene symbol: RTN4R. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q99M75 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RTN4R |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | cerebral cortex, glutamatergic |
| Annotated paper: | Zemmar A, et al. "Neutralization of Nogo-A enhances synaptic plasticity in the rodent motor cortex and improves motor learning in vivo" J Neurosci. 2014 Jun 25;34(26):8685-98 PMID:24966370 |
| Figure(s): | Fig. 1P, Table 1 |
| Annotation description: | Representative electron microscopic images showing Reticulon-4 receptor immunoreactive gold particles in the presynaptic compartment in the motor cortex. 24/11/2017 Pim - Most immunoparticles seem to be present on SVs. This annotation is not made because the presumed function is on the plasma membrane, but this is not shown in the paper. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| SynGO annotation ID: | 1968 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |