Annotated protein:Pleiotrophin (PTN) (Heparin-binding brain mitogen) (HBBM) (Heparin-binding growth factor 8) (HBGF-8) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding neutrophic factor) (HBNF) (Osteoblast-specific factor 1) (OSF-1). Gene symbol: PTN. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P63090
antibody wiki:
SynGO gene info:SynGO data @ PTN
Ontology domain:Cellular Component
SynGO term:presynapse (GO:0098793)
Synapse type(s):cerebral cortex
Annotated paper:Matsumoto K, et al. "A novel family of heparin-binding growth factors, pleiotrophin and midkine, is expressed in the developing rat cerebral cortex" Brain Res Dev Brain Res. 1994 Jun 17;79(2):229-41 PMID:7955321
Figure(s):Fig. 7E-F
Annotation description:Fig. 7 E,F show the localization of Pleiotrophin in axon terminals by electron microscopy using DAB staining in the P7 developing cortex.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Daniela Dieterich (ORCID:0000-0002-9880-1214)
Rainer Pielot (ORCID:0000-0002-9681-3318)
Karl-Heinz Smalla (ORCID:0000-0002-0269-0311)
Eckart Gundelfinger (ORCID:0000-0001-9377-7414)
Lab:Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany
SynGO annotation ID:1901
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology