Annotated protein: | Pleiotrophin (PTN) (Heparin-binding brain mitogen) (HBBM) (Heparin-binding growth factor 8) (HBGF-8) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding neutrophic factor) (HBNF) (Osteoblast-specific factor 1) (OSF-1). Gene symbol: PTN. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P63090 |
antibody wiki: | |
SynGO gene info: | SynGO data @ PTN |
Ontology domain: | Cellular Component |
SynGO term: | presynapse (GO:0098793) |
Synapse type(s): | cerebral cortex |
Annotated paper: | Matsumoto K, et al. "A novel family of heparin-binding growth factors, pleiotrophin and midkine, is expressed in the developing rat cerebral cortex" Brain Res Dev Brain Res. 1994 Jun 17;79(2):229-41 PMID:7955321 |
Figure(s): | Fig. 7E-F |
Annotation description: | Fig. 7 E,F show the localization of Pleiotrophin in axon terminals by electron microscopy using DAB staining in the P7 developing cortex. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
SynGO annotation ID: | 1901 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |