Annotated protein:Potassium voltage-gated channel subfamily A member 1 (RBKI) (RCK1) (Voltage-gated potassium channel subunit Kv1.1). Gene symbol: KCNA1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P10499
antibody wiki:
SynGO gene info:SynGO data @ KCNA1
Ontology domain:Biological Process
SynGO term:voltage-gated ion channel activity involved in regulation of presynaptic membrane potential (GO:0099508)
Annotated paper:Deal KK, et al. "The brain Kv1.1 potassium channel: in vitro and in vivo studies on subunit assembly and posttranslational processing" J Neurosci. 1994 Mar;14(3 Pt 2):1666-76 PMID:8126562
Figure(s):figure 4, figure 9
Annotation description:Expression of channels in Mouse L-cells (fybroblasts).

rule: NAS_MFCC-BP
rationale:
Protein has voltage-gated ion channel activity and is localized in teh presynaptic membrane (show with high-resolution technique). The inference to term 'voltage-gated ion channel activity involved in regulation of presynaptic membrane potential (GO:0099508)' is trivial and non-controversial.
Pinf_CC:
[P10499] SyNGO ID 179 (PMID:14614103, confocal)
Evidence tracking, Biological System:Non-neuronal tissue
Evidence tracking, Protein Targeting:Over-expression
Evidence tracking, Experiment Assay:Whole-cell patch clamp
Non-tracable Author Statement (NAS):This annotation required some inference over additional information/literature, and is not solely based on observations made in the annotated paper by its original authors.
Annotator(s):Niels Cornelisse (ORCID:0000-0001-9425-2935)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:187
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology