| Annotated protein: | TRAF2 and NCK interacting kinase. Gene symbol: TNIK. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: A0A0G2K490 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ TNIK |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Wang Q, et al. "The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function" Mol Psychiatry. 2011 Oct;16(10):1006-23 PMID:20838393 |
| Figure(s): | Fig 2C/D |
| Annotation description: | Fig 2D: "Electron microscopy provided further evidence that TNIK is present in dendritic spines and localized both to pre- and postsynaptic compartments, with enrichment in the latter (Figure 2d)." |
| Evidence tracking, Biological System: | Intact tissue Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Confocal |
| Annotator(s): | Chiara Verpelli (ORCID:0000-0003-2949-9725) Carlo Sala (ORCID:0000-0003-0662-9523) |
| Lab: | CNR Neuroscience Institute Milan and Dept. of Biotechnology and Translational Medicine, University of Milan, 20129 Milan, Italy |
| SynGO annotation ID: | 1847 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |