Annotated protein:Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (PTPNU-3) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma). Gene symbol: PTPRS. Taxonomy: Mus musculus (Mouse). Uniprot ID: B0V2N1
antibody wiki:
SynGO gene info:SynGO data @ PTPRS
Ontology domain:Biological Process
SynGO term:regulation of postsynaptic density assembly (GO:0099151)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Takahashi H, et al. "Postsynaptic TrkC and presynaptic PTPsigma function as a bidirectional excitatory synaptic organizing complex" Neuron. 2011 Jan 27;69(2):287-303 PMID:21262467
Figure(s):Fig.4
Annotation description:Fig.4: TrkC and PTPσ Ectodomains Induce Excitatory Presynaptic and Postsynaptic Differentiation, Respectively
Evidence tracking, Biological System:Intact tissue
Cultured neurons
Evidence tracking, Protein Targeting:Over-expression
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Chiara Verpelli (ORCID:0000-0003-2949-9725)
Carlo Sala (ORCID:0000-0003-0662-9523)
Lab:CNR Neuroscience Institute Milan and Dept. of Biotechnology and Translational Medicine, University of Milan, 20129 Milan, Italy
SynGO annotation ID:1846
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology