Annotated protein:Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (EC 3.2.2.6) (Interleukin-33 receptot beta chain). Gene symbol: IL1RAP. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q61730-3
antibody wiki:
SynGO gene info:SynGO data @ IL1RAP
Ontology domain:Biological Process
SynGO term:trans-synaptic signaling by trans-synaptic complex (GO:0099545)
Synapse type(s):cerebral cortex, glutamatergic
Annotated paper:Yoshida T, et al. "Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule" J Neurosci. 2012 Feb 22;32(8):2588-600 PMID:22357843
Figure(s):Fig.8
Annotation description:Fig.8 IL-1RAcPb and IL-1RAcP (not shown) requires PTPδ for presynaptic differentiation
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:Over-expression
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Chiara Verpelli (ORCID:0000-0003-2949-9725)
Carlo Sala (ORCID:0000-0003-0662-9523)
Lab:CNR Neuroscience Institute Milan and Dept. of Biotechnology and Translational Medicine, University of Milan, 20129 Milan, Italy
SynGO annotation ID:1830
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology