Annotated protein:Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8). Gene symbol: HSPA8. Taxonomy: Mus musculus (Mouse). Uniprot ID: P63017
antibody wiki:
SynGO gene info:SynGO data @ HSPA8
Ontology domain:Cellular Component
SynGO term:presynapse (GO:0098793)
Synapse type(s):Photoreceptor ribbon synapse
Annotated paper:Fuchs M, et al. "Evidence for a Clathrin-independent mode of endocytosis at a continuously active sensory synapse" Front Cell Neurosci. 2014 Feb 25;8:60 PMID:24616664
Figure(s):figure 1
Annotation description:In figure 1 the authors perform immunofluorescence analysis of ribbon synapses in the mouse retina. Hsc70 (figure 1E) localizes to the inner and outer plexiform layers, characteristic of a presynaptic protein
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Peter McPherson (ORCID:0000-0001-7806-5662)
Lab:Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada
SynGO annotation ID:1761
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology