| Annotated protein: | Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4). Gene symbol: SH3GL2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: O35179 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SH3GL2 |
| Ontology domain: | Cellular Component |
| SynGO term: | synapse (GO:0045202) |
| Synapse type(s): | Schaffer collateral synapse (CA3->CA1) Mossy fiber synapse (DG->CA3) |
| Annotated paper: | Ringstad N, et al. "Differential expression of endophilin 1 and 2 dimers at central nervous system synapses" J Biol Chem. 2001 Nov 2;276(44):40424-30 PMID:11518713 |
| Figure(s): | figure 7 and 8 |
| Annotation description: | The authors performed conventional confocal microscopy using antibodies against endophilin 1. They demonstrate colocalization of endophilin 1 with the presynaptic marker synaptophysin in both cultured rat hippocampal neurons (figure 7) and rat brain sections (figure 8) (deep cerebellar nuclei, CA1 region and CA3 region) |
| Evidence tracking, Biological System: | Intact tissue Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Peter McPherson (ORCID:0000-0001-7806-5662) |
| Lab: | Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada |
| SynGO annotation ID: | 1701 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |