| Annotated protein: | Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3). Gene symbol: KCNC3. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q01956 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ KCNC3 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of presynaptic membrane (GO:0099056) |
| Synapse type(s): | cerebellum, glutamatergic |
| Annotated paper: | Puente N, et al. "Precise localization of the voltage-gated potassium channel subunits Kv3.1b and Kv3.3 revealed in the molecular layer of the rat cerebellar cortex by a pre-embedding immunogold method" Histochem Cell Biol. 2010 Oct;134(4):403-9 PMID:20857303 |
| Figure(s): | fig 2 |
| Annotation description: | Discrete labeling is visualised along membranes of both parallel fiber terminals and typical thin intervaricose segments of parallel fiber axons 5/12/2016 Pim - Literal Fig 2; "Discrete labeling is visualized along the membranes of both parallel fiber terminals (small arrows in a and e) and typical thin intervaricose segments of parallel fiber axons (ax in a , c - f). Note that active zones are devoid of silver particles (arrowheads in a - e). " - integral component in the annotation is derived from TM-domains in the annotated protein. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 17 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |