| Annotated protein: | Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein). Gene symbol: NEFL. Taxonomy: Mus musculus (Mouse). Uniprot ID: P08551 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ NEFL |
| Ontology domain: | Cellular Component |
| SynGO term: | presynaptic intermediate filament cytoskeleton (GO:0099182) |
| Synapse type(s): | Neuro-muscular junction |
| Annotated paper: | Roche SL, et al. "Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction" J Neurosci. 2014 Sep 17;34(38):12904-18 PMID:25232125 |
| Figure(s): | Fig.9 |
| Annotation description: | This figure shows that neurofilament light chain (NF-L) can be detected by immunofluorescence in presynaptic terminals of the neuromuscular junction in mice. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Jan van Weering (ORCID:0000-0001-5259-4945) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 1687 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |