| Annotated protein: | Large ribosomal subunit protein eL22 (60S ribosomal protein L22) (Heparin-binding protein HBp15). Gene symbol: RPL22. Taxonomy: Mus musculus (Mouse). Uniprot ID: P67984 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RPL22 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynaptic ribosome |
| Synapse type(s): | retina, glutamatergic |
| Annotated paper: | Shigeoka T, et al. "Dynamic Axonal Translation in Developing and Mature Visual Circuits" Cell. 2016 Jun 30;166(1):181-92 PMID:27321671 |
| Figure(s): | Fig. 1K,L |
| Annotation description: | The paper uses the RiboTag-mouse (epitope tagged mouse RPL22) to visualize axonal translation in the visual system. Fig. 1 shows the localization of RPL22 (via HA-tag) in axon terminals of the superior colliculus (in retina). 13/10/2017 Pim - Localization to ribosomes is not shown directly but inferred from well established role of RPL22 as ribosomal protein and author intent. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Wide-field fluorescence |
| Annotator(s): | Daniela Dieterich (ORCID:0000-0002-9880-1214) Rainer Pielot (ORCID:0000-0002-9681-3318) Karl-Heinz Smalla (ORCID:0000-0002-0269-0311) Eckart Gundelfinger (ORCID:0000-0001-9377-7414) |
| Lab: | Leibniz Institute for Neurobiology (LIN), Institute of Pharmacology and Toxicology, Otto von Guericke University, Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany |
| SynGO annotation ID: | 1681 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |