| Annotated protein: | Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain). Gene symbol: KALRN. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P97924 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ KALRN |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | cerebrum |
| Annotated paper: | Boyken J, et al. "Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses" Neuron. 2013 Apr 24;78(2):285-97 PMID:23622064 |
| Figure(s): | Table S1 |
| Annotation description: | Quantitative mass spectrometric analyses (iTRAQ) of synaptic vesicle docking complexes indicate the presence of KALRN on presynaptic terminals. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | none of the above |
| Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
| Annotator(s): | John Chua (ORCID:0000-0002-5615-1014) |
| Lab: | Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Neurobiology/Ageing Program, Life Sciences Institute, National University of Singapore and Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore |
| Additional literature: | Mass spectrometric analyses of FACS purified glutamatergic synaptosomes from mouse brains indicate the presence of KALRN on synaptosomes. @ PMID:24413018 |
| SynGO annotation ID: | 1669 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |