| Annotated protein: | Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1). Gene symbol: DVL1. Taxonomy: Mus musculus (Mouse). Uniprot ID: P51141 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ DVL1 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynapse (GO:0098793) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Ahmad-Annuar A, et al. "Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release" J Cell Biol. 2006 Jul 3;174(1):127-39 PMID:16818724 |
| Figure(s): | Figs 1 and 2 |
| Annotation description: | Fluorescence microscopy of endogenous Dvl1 or over-expressed Dvl1 in hippocampal neurons (Div 9) show appreciable punctate colocalisation with presynaptic markers synapsin-1 and Bassoon along axons. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Over-expression Antibody (detection) |
| Evidence tracking, Experiment Assay: | Wide-field fluorescence |
| Annotator(s): | John Chua (ORCID:0000-0002-5615-1014) |
| Lab: | Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Neurobiology/Ageing Program, Life Sciences Institute, National University of Singapore and Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore |
| SynGO annotation ID: | 1668 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |