Annotated protein: | Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66). Gene symbol: INA. Taxonomy: Mus musculus (Mouse). Uniprot ID: P46660 |
antibody wiki: | |
SynGO gene info: | SynGO data @ INA |
Ontology domain: | Cellular Component |
SynGO term: | postsynapse (GO:0098794) |
Synapse type(s): | striatum neocortex |
Annotated paper: | Yuan A, et al. "Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo" Mol Psychiatry. 2015 Aug;20(8):986-94 PMID:25869803 |
Figure(s): | Fig1, FigS2 and Fig2 |
Annotation description: | Fig1 shows by quantitative immunoEM that α-internexin is mainly present in the postsynapse. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Jan van Weering (ORCID:0000-0001-5259-4945) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 1652 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |