| Annotated protein: | Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3). Gene symbol: KCNC3. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q01956 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ KCNC3 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of postsynaptic membrane (GO:0099055) |
| Synapse type(s): | cerebellum, glutamatergic |
| Annotated paper: | Puente N, et al. "Precise localization of the voltage-gated potassium channel subunits Kv3.1b and Kv3.3 revealed in the molecular layer of the rat cerebellar cortex by a pre-embedding immunogold method" Histochem Cell Biol. 2010 Oct;134(4):403-9 PMID:20857303 |
| Figure(s): | fig 2 |
| Annotation description: | Purkinje cell dendritic spines (sp) receiving asymmetrical synapses from parallel fiber terminals (PFT) are Kv3.3 immunopositive. 5/12/2016 Pim - The integral component of the annotation was derived from the TM-domains of KCNC3. - Literal Fig.2: "Purkinje cell dendritic spines ( sp ) receiving asymmetrical synapses from parallel fiber terminals ( PFT ) are Kv3.3 immunopositive ( arrows in a - e ). Silver particles are positioned perisynaptically but also in **extrasynaptic positions ( arrows in a - e ) along the spine membranes**." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 16 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |