| Annotated protein: | Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (dC stretch-binding protein) (CSBP). Gene symbol: HNRNPK. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P61980 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ HNRNPK |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Folci A, et al. "Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons" J Neurosci. 2014 Jul 2;34(27):9088-95 PMID:24990929 |
| Figure(s): | Fig. 1A |
| Annotation description: | hnRNP K localised is enriched in dendritic spines of primary rat hippocampal neurons (div 18). Since the overlap with PSD-95 staining is better than with VGLUT staining, the signal is assumed to be post-synaptic. 25/9/2017 Pim - Literal: "In hippocampal neurons, hnRNP K was detected in the dendritic spines and colocalized with the presynaptic protein VGLUT1 and the postsynaptic scaffolding protein PSD-95" |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Alexandros Kanellopoulos (ORCID:0000-0002-2094-7491) Vittoria Mariano (ORCID:0000-0002-9848-0262) Achsel Tilmann (ORCID:0000-0002-1190-4481) Claudia Bagni (ORCID:0000-0002-4419-210X) |
| Lab: | Department of Fundamental Neurosciences, University of Lausanne, CH-1006 Lausanne, Switzerland; Dept Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy |
| Additional literature: | localised in neurites of primary neurons (rat hippocampus; DIV 12): Fig 4A @ PMID:22102872 |
| SynGO annotation ID: | 1596 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |