| Annotated protein: | Eukaryotic translation initiation factor 4 gamma, 1. Gene symbol: EIF4G1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: D4AD15 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ EIF4G1 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | hippocampus |
| Annotated paper: | Wang H, et al. "Dendritic BC1 RNA: functional role in regulation of translation initiation" J Neurosci. 2002 Dec 1;22(23):10232-41 PMID:12451124 |
| Figure(s): | fig 6A |
| Annotation description: | eIF4G (G1 isoform according to cited paper) is present in the dendritic compartment of primary hippocampal neurons and juxtaposed to synaptophysin. 26/9/2017 Pim - Literal: " Some, but not all, apposing red/green puncta pairs apparently overlapped to some degree, evidenced by narrow yellow interface areas. Because green puncta identify axonal presynaptic specializations, it is concluded that such apposing red clusters correlate with postsynaptic dendritic compartments." |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Alexandros Kanellopoulos (ORCID:0000-0002-2094-7491) Vittoria Mariano (ORCID:0000-0002-9848-0262) Achsel Tilmann (ORCID:0000-0002-1190-4481) Claudia Bagni (ORCID:0000-0002-4419-210X) |
| Lab: | Department of Fundamental Neurosciences, University of Lausanne, CH-1006 Lausanne, Switzerland; Dept Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy |
| SynGO annotation ID: | 1590 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |