| Annotated protein: | Potassium voltage-gated channel subfamily C member 1 (NGK2) (RAW2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4). Gene symbol: KCNC1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P25122 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ KCNC1 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of presynaptic membrane (GO:0099056) |
| Synapse type(s): | cerebellum |
| Annotated paper: | Puente N, et al. "Precise localization of the voltage-gated potassium channel subunits Kv3.1b and Kv3.3 revealed in the molecular layer of the rat cerebellar cortex by a pre-embedding immunogold method" Histochem Cell Biol. 2010 Oct;134(4):403-9 PMID:20857303 |
| Figure(s): | fig 1a-d |
| Annotation description: | immunogold-silver particles are observed (arrows) in membranes of parallel fiber synaptic terminals 5/12/2016 Pim - integral component in the annotation is derived from TM-domains in the annotated protein. - Literal Fig1 "Many immunogold-silver particles are observed (arrows) in membranes of parallel fiber synaptic terminals (PFT in a-d) making asymmetrical synapses with immunonegative Purkinje cell dendritic spines (sp)." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 15 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |