| Annotated protein: | IQ motif and SEC7 domain-containing protein 3. Gene symbol: IQSEC3. Taxonomy: Mus musculus (Mouse). Uniprot ID: Q3TES0 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ IQSEC3 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynaptic specialization of symmetric synapse (GO:0099629) |
| Synapse type(s): | cerebellum olfactory bulb |
| Annotated paper: | Fukaya M, et al. "SynArfGEF is a guanine nucleotide exchange factor for Arf6 and localizes preferentially at post-synaptic specializations of inhibitory synapses" J Neurochem. 2011 Mar;116(6):1122-37 PMID:21198641 |
| Figure(s): | Fig.5 |
| Annotation description: | Fig5 shows immunoEM of IQSEC3 (synArfGEF). Immunogold is selectively detected at the post-synaptic specialisation membrane of symmetric synapses. No quantification is offered. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Jan van Weering (ORCID:0000-0001-5259-4945) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 1378 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |