| Annotated protein: | Epsin 1. Gene symbol: . Taxonomy: Lampetra fluviatilis (European river lamprey). Uniprot ID: B2MVI1 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ EPN1 |
| Ontology domain: | Cellular Component |
| SynGO term: | extrinsic component of presynaptic endocytic zone membrane (GO:0098894) |
| Annotated paper: | Jakobsson J, et al. "Role of epsin 1 in synaptic vesicle endocytosis" Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6445-50 PMID:18430801 |
| Figure(s): | fig 2 |
| Annotation description: | In figure 2, the authors mention "We characterized a lamprey ortholog of epsin 1 and showed that it is accumulated at release sites at rest and also at clathrin-coated pits in the periactive zone during synaptic activity". This is justified to make the annotation 'extrinsic component of presynaptic endocytic zone membrane (GO:0098894)' (confocal+immuno-EM). |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy Confocal |
| Annotator(s): | Peter McPherson (ORCID:0000-0001-7806-5662) |
| Lab: | Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada |
| SynGO annotation ID: | 1362 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |