Annotated protein:RAB5C, member RAS oncogene family. Gene symbol: RAB5C. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: B0BNK1
antibody wiki:
SynGO gene info:SynGO data @ RAB5C
Ontology domain:Cellular Component
SynGO term:anchored component of synaptic vesicle membrane (GO:0098993)
Synapse type(s):cerebrum
Annotated paper:Pavlos NJ, et al. "Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis" J Neurosci. 2010 Oct 6;30(40):13441-53 PMID:20926670
Figure(s):Table 1
Annotation description:Rab5C was identified on highly purified synaptic vesicles using mass spectrometry in two separate studies (Pavlos et al., 2010; Takamori et al., 2006).
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:none of the above
Evidence tracking, Experiment Assay:Mass-spectrometry
Biochemical fractionation (generic)
Annotator(s):John Chua (ORCID:0000-0002-5615-1014)
Lab:Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Neurobiology/Ageing Program, Life Sciences Institute, National University of Singapore and Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore
Additional literature:Rab5C was identified on highly purified synaptic vesicles using mass spectrometry @ PMID:17110340
SynGO annotation ID:134
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology