| Annotated protein: | Large ribosomal subunit protein uL2 (60S ribosomal protein L8). Gene symbol: RPL8. Taxonomy: Homo sapiens (Human). Uniprot ID: P62917 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ RPL8 |
| Ontology domain: | Cellular Component |
| SynGO term: | postsynapse (GO:0098794) |
| Synapse type(s): | cerebral cortex |
| Annotated paper: | Bayes A, et al. "Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins" PLoS One. 2012;7(10):e46683 PMID:23071613 |
| Figure(s): | Table S1-S2 |
| Annotation description: | PSD fractionation |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Mass-spectrometry |
| Annotator(s): | Alexandros Kanellopoulos (ORCID:0000-0002-2094-7491) Vittoria Mariano (ORCID:0000-0002-9848-0262) Achsel Tilmann (ORCID:0000-0002-1190-4481) Claudia Bagni (ORCID:0000-0002-4419-210X) |
| Lab: | Department of Fundamental Neurosciences, University of Lausanne, CH-1006 Lausanne, Switzerland; Dept Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy |
| Additional literature: | We isolated hPSD from neocortical biopsies of nine adults (Supplementary Table 1 and Supplementary Fig. 1a) and performed proteomic profiling using LC-MS/MS to comprehensively identify a total of 1,461 proteins (total hPSD), 748 of which were detected in all three replicates (consensus hPSD, used for all subsequent analysis, except where explicitly stated otherwise; Supplementary Table 2). @ PMID:21170055 |
| SynGO annotation ID: | 1318 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |