| Annotated protein: | Potassium voltage-gated channel subfamily A member 4 (RCK4) (RHK1) (RK3) (Voltage-gated potassium channel subunit Kv1.4). Gene symbol: KCNA4. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P15385 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ KCNA4 |
| Ontology domain: | Cellular Component |
| SynGO term: | integral component of presynaptic membrane (GO:0099056) |
| Synapse type(s): | neocortex, glutamatergic hippocampus, glutamatergic |
| Annotated paper: | Lujan R, et al. "Immunohistochemical localization of the voltage-gated potassium channel subunit Kv1.4 in the central nervous system of the adult rat" J Chem Neuroanat. 2003 Nov;26(3):209-24 PMID:14615029 |
| Figure(s): | fig 8G-J |
| Annotation description: | Potassium channel localised in presynaptic membrane specialisation. 5/12/2016 Pim - Literal Fig 8: "At presynaptic level, immunoparticles for Kv1.4 were observed in boutons of pyramidal cell axons (b) extrasynaptically (double arrows) and in presynaptic membrane specialization (double arrowheads) of synapses on spines (s)" - Presynaptic localization is shown for neocortex (Fig 8I) and hippocampus (Fig.8J) [see double arrowheads] - integral component in the annotation is derived from TM-domains in the annotated protein. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 13 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |