Annotated protein: | RAB5B, member RAS oncogene family. Gene symbol: RAB5B. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: A1L1J8 |
antibody wiki: | |
SynGO gene info: | SynGO data @ RAB5B |
Ontology domain: | Cellular Component |
SynGO term: | anchored component of synaptic vesicle membrane (GO:0098993) |
Synapse type(s): | cerebrum |
Annotated paper: | Pavlos NJ, et al. "Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis" J Neurosci. 2010 Oct 6;30(40):13441-53 PMID:20926670 |
Figure(s): | Table 1 |
Annotation description: | Rab5B was identified on highly purified synaptic vesicles using mass spectrometry by two separate studies (Pavlos et al., 2010; Takamori et al., 2006). |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | none of the above |
Evidence tracking, Experiment Assay: | Mass-spectrometry Biochemical fractionation (generic) |
Annotator(s): | John Chua (ORCID:0000-0002-5615-1014) |
Lab: | Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Neurobiology/Ageing Program, Life Sciences Institute, National University of Singapore and Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore |
Additional literature: | Rab5B was identified on highly purified synaptic vesicles using mass spectrometry @ PMID:17110340 |
SynGO annotation ID: | 127 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |