Annotated protein: | Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4). Gene symbol: GRIA4. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P19493 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GRIA4 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of presynaptic active zone membrane (GO:0099059) |
Synapse type(s): | striatum, glutamatergic |
Annotated paper: | Fujiyama F, et al. "Presynaptic localization of an AMPA-type glutamate receptor in corticostriatal and thalamostriatal axon terminals" Eur J Neurosci. 2004 Dec;20(12):3322-30 PMID:15610164 |
Figure(s): | fig.3d-g |
Annotation description: | GluR4 detection with immuno EM in presynaptic glutamatergic terminals in neostriatum 8/9/2017 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 1204 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |