Annotated protein:Glutamate receptor 3 (GluR-3) (AMPA-selective glutamate receptor 3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (GluA3). Gene symbol: GRIA3. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P19492
antibody wiki:
SynGO gene info:SynGO data @ GRIA3
Ontology domain:Cellular Component
SynGO term:integral component of postsynaptic membrane (GO:0099055)
Synapse type(s):cerebral cortex
Annotated paper:Feligioni M, et al. "Ultrastructural localisation and differential agonist-induced regulation of AMPA and kainate receptors present at the presynaptic active zone and postsynaptic density" J Neurochem. 2006 Oct;99(2):549-60 PMID:16903873
Figure(s):Fig.5-6
Annotation description:GluR3 measured with western blot in presynaptic synaptosome fractions.

8/9/2017 Pim
- Experiments involve quantification of plasma membrane/surface levels of receptors via biotinylation assay.
- Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen.
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Western blot
Biochemical fractionation (generic)
Annotator(s):Niels Cornelisse (ORCID:0000-0001-9425-2935)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:1200
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology