Annotated protein: | Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2). Gene symbol: GRIA2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P19491 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GRIA2 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of presynaptic active zone membrane (GO:0099059) |
Synapse type(s): | Schaffer collateral synapse (CA3->CA1) |
Annotated paper: | Haglerod C, et al. "Presynaptic PICK1 facilitates trafficking of AMPA-receptors between active zone and synaptic vesicle pool" Neuroscience. 2017 Mar 6;344:102-112 PMID:28057533 |
Figure(s): | Fig. 3A,C-D |
Annotation description: | Immuno EM of presynaptic AMPA receptor subunit 2 in HC neurons |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 1194 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |