Annotated protein:Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2). Gene symbol: GRIA2. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P19491
antibody wiki:
SynGO gene info:SynGO data @ GRIA2
Ontology domain:Cellular Component
SynGO term:integral component of presynaptic active zone membrane (GO:0099059)
Synapse type(s):Schaffer collateral synapse (CA3->CA1)
Annotated paper:Haglerod C, et al. "Presynaptic PICK1 facilitates trafficking of AMPA-receptors between active zone and synaptic vesicle pool" Neuroscience. 2017 Mar 6;344:102-112 PMID:28057533
Figure(s):Fig. 3A,C-D
Annotation description:Immuno EM of presynaptic AMPA receptor subunit 2 in HC neurons
Evidence tracking, Biological System:Intact tissue
Evidence tracking, Protein Targeting:Antibody (detection)
Evidence tracking, Experiment Assay:Electron Microscopy
Annotator(s):Niels Cornelisse (ORCID:0000-0001-9425-2935)
Matthijs Verhage (ORCID:0000-0002-2514-0216)
Lab:Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands
SynGO annotation ID:1194
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology